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Recombinant human HGD protein

Cat:P05695

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 10-360aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: HGD
【Full Name】: homogentisate 1,2-dioxygenase (homogentisate oxidase)
【Uniprot】: Q93099
【Gene ID】: 3081
【Species Reactivity】: Human Mouse
【Mol Mass】: 39.5kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

This gene encodes the enzyme homogentisate 1,2 dioxygenase. This enzyme is involved in the catabolism of the amino acids tyrosine and phenylalanine. Mutations in this gene are the cause of the autosomal recessive metabolism disorder alkaptonuria.

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