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Recombinant human DSCC1 protein

Cat:P05908

Summary:

【Derived From】: E.coli
【Endotoxin】: Not measured
【Amino Acid】: 41-394aa
【Purity】: ≥85% by SDS-PAGE.
【Name】: DSCC1
【Full Name】: defective in sister chromatid cohesion 1 homolog (S. cerevisiae)
【Uniprot】: Q9BVC3
【Gene ID】: 79075
【Species Reactivity】: Human Mouse (ZebraFish)
【Mol Mass】: 41kDa
【Application】: Immunology research
【Purification】: NI-NTA affinity purification
【Bioactive】: N0
【Tag】: With a 6×His tag at the N/C-terminus.
【Concentration】: 1mg/ml by SDS-PAGE.

Store:

【Reconstitution】: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
【Storage】: Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year.
【Formulation】: Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0.

Background:

Loads PCNA onto primed templates regulating velocity, spacing and restart activity of replication forks. May couple DNA replication to sister chromatid cohesion through regulation of the acetylation of the cohesin subunit SMC3.

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