Summary:
Recombinant human GABARAPL1 protein
Cat：P06080
| 【Derived From】： E.coli |
| 【Endotoxin】： Not measured |
| 【Amino Acid】： 1-118aa |
| 【Purity】： ≥85% by SDS-PAGE. |
| 【Name】： GABARAPL1 |
| 【Full Name】： GABA(A) receptor-associated protein like 1 |
| 【Uniprot】： Q9H0R8 |
| 【Gene ID】： 23710 |
| 【Species Reactivity】： Human Mouse Rat (Bovine) |
| 【Mol Mass】： 14kDa |
| 【Application】： Immunology research |
| 【Purification】： NI-NTA affinity purification |
| 【Bioactive】： N0 |
| 【Tag】： With a 6×His tag at the N/C-terminus. |
| 【Concentration】： 1mg/ml by SDS-PAGE. |
Store:
| 【Reconstitution】： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 【Storage】： Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| 【Formulation】： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Background:
Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor (PubMed:16431922).Involved in formation of autophagosomal vacuoles (PubMed:20404487).While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamilyis essential for a later stage in autophagosome maturation (PubMed:20404487).Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover (PubMed:31006538, PubMed:31006537).
Verified picture
