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CAS:57-57-8
Appearance:Colourless transparent solution
Storage:-20℃
Purity:98%
β-propanolactone (BPL) is easy to hydrolysis, no residue, no harm after hydrolysis; It can directly act on virus or pathogen nucleic acid, and the inactivation effect is ideal. The short inactivation time can shorten the vaccine production cycle. Therefore, since the use of β-propanolactone as a rabies vaccine inactivator in 1984, it has been successfully and widely used in the production of a variety of human and animal vaccines. Solarbio integrates global resources to provide many vaccine manufacturers with high-quality β-propanolactone products with the following advantages:
The product was detected by 1H-NMR (GC method could not detect the polymer) to ensure that there was no polymer, and the purity was ≥98.5%, which could fully meet the inactivation requirements of vaccine production
Sufficient stock, stable inventory and timely supply can ensure smooth production of scientific research and enterprises
Diversified packaging specifications can meet the needs of various stages such as experiment, pilot, pilot and large-scale production
Features:
1. Direct action on viral nucleic acid, maintain immunogenicity, strong inactivation effect. β-propanolactone (BPL) directly interacts with viral nucleic acids, but does not act on shell proteins, and does not destroy the immunogenicity of pathogens.
2. Easily hydrolyzed, no residue, and the hydrolyzed products are non-toxic and harmless. Although large dose β-propanolactone (BPL) is a carcinogen, it is easily hydrolyzed and disappears after 2h hydrolysis in 37℃ water bath, and it is hydrolyzed to non-toxic human fat metabolite β-hydroxypropionic acid. In addition, because it can be completely hydrolyzed in the vaccine liquid, residue in the finished vaccine does not need to be considered.
3. The inactivation time is short, shortening the vaccine production cycle. β-propanolactone can be completely hydrolyzed in only 2 hours, and the inactivation time is short, thus significantly shortening the vaccine production cycle and improving economic benefits.
β-propanolactone is also used as an intermediate in drugs, resins and fiber modifiers, and its derivative β-mercaptopropionic acid is a raw material for PVC stabilizers and pharmaceuticals.
Storage conditions: Away from fire, sealed, -20°C, dark, ventilated, dry
Note：Product information may be optimized and upgraded. Please refer to the actual label information for accuracy.
