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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Neuronal Signal Pathway > ARN2966CAS：102212-26-0
Molecular Formula：C12H12N2O
Molecular Weight：200.24
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 102212-26-0 |
| Name | ARN2966 |
| Molecular Formula | C12H12N2O |
| Molecular Weight | 200.24 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | C1=CC=C(C(=C1)NCC2=CC=CC=N2)O |
| InChIKey | GXJRVWZNMZGWAQ-UHFFFAOYSA-N |
| InChI | InChI=1S/C12H12N2O/c15-12-7-2-1-6-11(12)14-9-10-5-3-4-8-13-10/h1-8，14-15H，9H2 |
| PubChem CID | 14936865 |
| Target Point | Amyloid-β |
| Passage | Neuronal Signaling |
| Background | ARN2966 is A highly effective post-transcriptional regulator of APP expression, which reduces the expression of APP and thus the amount of Aβ. |
| Biological Activity | ARN2966 is a potent post-transcriptional modulator of amyloid precursor protein (APP) expression in transfected CHO cells. The CHO cell can produce APP.[1] |
| Data Literature Source | [1] Ayodeji Asuni ，Xu Kevin ，etal. ，An APP translation modulator ARN2966 reduces BETA-AMYLOID deposition and prevents memory deficits in ALZHEIMER'S DISEASE transgenic mice. Alzheimer's & Dementia: The Journal of the Alzheimer's Association，July 2012Volume 8，Issue 4，Supplement，Page S744 ; |
| Unit | Bottle |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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