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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Membrane Transporter & Ion Channel > Esomeprazole MagnesiumCAS：161973-10-0
Molecular Formula：C34H36MgN6O6S2
Molecular Weight：713.12
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 161973-10-0 |
| Name | Esomeprazole Magnesium |
| Molecular Formula | C34H36MgN6O6S2 |
| Molecular Weight | 713.12 |
| Solubility | Soluble in DMSO ≥10mg/mL |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD06798050 |
| SMILES | CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C([N-]2)C=CC(=C3)OC.CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C([N-]2)C=CC(=C3)OC.[Mg+2] |
| InChIKey | KWORUUGOSLYAGD-UHFFFAOYSA-N |
| InChI | InChI=1S/2C17H18N3O3S.Mg/c2*1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;/h2*5-8H，9H2，1-4H3;/q2*-1;+2 |
| PubChem CID | 130564 |
| Target Point | Proton Pump |
| Passage | Membrane Transporter&Ion Channel |
| Background | Esomeprazole magnesium is a type of H+, K+-ATPase (a type of proton pump) inhibitor or exosome inhibitor that blocks the release of exosomes by inhibiting V-H+-ATPases. |
| Biological Activity | Esomeprazole Magnesium是一种强效的口服活性 H+、K+-ATPase 抑制剂。可用于上消化道疾病和胃食管反流病的研究，通过抑制 V-H+-ATP 酶阻断外泌体的释放，从而起到外泌体抑制剂的作用。[1-3] |
| Data Literature Source | [1]. Koch TR，et al. Effect of the H，K-ATPase inhibitor，esomeprazole magnesium，on gut total antioxidant capacity in mice. J Nutr Biochem. 2004 Sep;15(9): 522-6. [2]. Kumar P，et al. Preparation and characterization of pH-sensitive methyl methacrylate-g-starch/hydroxypropylated starch hydrogels: in vitro and in vivo study on release of esomeprazole magnesium. Drug Deliv Transl Res. 2015 Jun;5(3): 243-56. [3]. Zhang H，et al. Advances in the discovery of exosome inhibitors in cancer. J Enzyme Inhib Med Chem. 2020 Dec;35(1): 1322-1330. |
| Unit | Bottle |
| Specification | 25mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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