{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Neuronal Signal Pathway > CinchonidineCAS：485-71-2
Molecular Formula：C19H22N2O
Molecular Weight：294.39
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：T≥98%
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 485-71-2 |
| Name | Cinchonidine |
| Molecular Formula | C19H22N2O |
| Molecular Weight | 294.39 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | T≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 207-622-3 |
| MDL | MFCD00006783 |
| SMILES | C=CC1CN2CCC1CC2C(C3=CC=NC4=CC=CC=C34)O |
| InChIKey | KMPWYEUPVWOPIM-KODHJQJWSA-N |
| InChI | InChI=1S/C19H22N2O/c1-2-13-12-21-10-8-14(13)11-18(21)19(22)16-7-9-20-17-6-4-3-5-15(16)17/h2-7，9，13-14，18-19，22H，1，8，10-12H2/t13-，14-，18-，19+/m0/s1 |
| PubChem CID | 101744 |
| Target Point | Serotonin Transporter |
| Passage | Neuronal Signaling |
| Background | It is a weak inhibitor of serotonin transporter (SERT) and has antimalarial activity. |
| Biological Activity | Cinchonidine 是一种金鸡纳生物碱，存在于 Cinchona officinalis 和 Gongronema latifolium 中。是有机化学中用于不对称合成的构件。5-羟色胺转运体（SERT）的弱抑制剂，dSERT、hSERT、hSERT I172M、hSERT S438T 和 hSERT Y95F 的 Kis 值分别为 330、4.2、36、196 和 15 μM。[1] |
| Data Literature Source | [1]. Beckman ML，et al. Stereoselective inhibition of serotonin transporters by antimalarial compounds. Neurochem Int. 2014 Jul;73: 98-106. |
| Unit | Bottle |
| Specification | 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
