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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Endocrinology & Hormones > Esmolol HydrochlorideCAS：81161-17-3
Molecular Formula：C16H26ClNO4
Molecular Weight：331.83
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 81161-17-3 |
| Name | Esmolol Hydrochloride |
| Molecular Formula | C16H26ClNO4 |
| Molecular Weight | 331.83 |
| Solubility | Soluble in Water/DMSO ≥5mg/mL |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00941432 |
| SMILES | CC(C)NCC(COC1=CC=C(C=C1)CCC(=O)OC)O.Cl |
| InChIKey | GEKNCWBANDDJJL-UHFFFAOYSA-N |
| InChI | InChI=1S/C16H25NO4.ClH/c1-12(2)17-10-14(18)11-21-15-7-4-13(5-8-15)6-9-16(19)20-3;/h4-5，7-8，12，14，17-18H，6，9-11H2，1-3H3;1H |
| PubChem CID | 104769 |
| Target Point | Adrenergic Receptor |
| Passage | Endocrinology & Hormones;GPCR & G Protein；Neuronal Signaling |
| Background | It is a beta adrenergic receptor inhibitor. |
| Biological Activity | Esmolol Hydrochloride 是一种肾上腺素受体阻滞剂，用于控制心跳急或异常心率节律。[1] |
| Data Literature Source | [1]. Wiest D. Esmolol. A review of its therapeutic efficacy and pharmacokinetic characteristics. Clin Pharmacokinet. 1995 Mar;28(3):190-202. [2]. Suzuki T，et al. Infusion of the beta-adrenergic blocker esmolol attenuates myocardial dysfunction in septic rats. Crit Care Med. 2005 Oct;33(10):2294-301. [3]. Sasao J，et al. In rabbits，landiolol，a new ultra-short-acting beta-blocker，exerts a more potent negative chronotropic effect and less effect on blood pressure than esmolol. Can J Anaesth. 2001 Nov;48(10):985-9. [4]. Sugiyama A，et al. Electrophysiologic，cardiohemodynamic and beta-blocking actions of a new ultra-short-acting beta-blocker，ONO-1101，assessed by the in vivo canine model in comparison with esmolol. J Cardiovasc Pharmacol. 1999 Jul;34(1):70-7. |
| Unit | Bottle |
| Specification | 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
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