{{cart_num}}
My Cart> Small Molecule Compounds > Anti-Infection > Anti-Bacterial > Imipenem MonohydrateCAS：74431-23-5
Molecular Formula：C12H19N3O5S
Molecular Weight：317.36
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
Qty：
Size：
| CAS | 74431-23-5 |
| Name | Imipenem Monohydrate |
| Molecular Formula | C12H19N3O5S |
| Molecular Weight | 317.36 |
| Solubility | Soluble in Water(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 264-734-5 |
| MDL | MFCD09753321 |
| SMILES | CC(C1C2CC(=C(N2C1=O)C(=O)O)SCCN=CN)O.O |
| InChIKey | GSOSVVULSKVSLQ-JJVRHELESA-N |
| InChI | InChI=1S/C12H17N3O4S.H2O/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17;/h5-7，9，16H，2-4H2，1H3，(H2，13，14)(H，18，19);1H2/t6-，7-，9-;/m1./s1 |
| PubChem CID | 5282372 |
| Target Point | Bacterial |
| Passage | Anti-infection |
| Background | It is an antibiotic with good resistance to Gram-positive and Gram-negative aerobic and anaerobic bacteria. |
| Biological Activity | Imipenem Monohydrate 是噻那霉素的一种稳定结晶衍生物，是一种抗生素，对多种革兰氏阳性和革兰氏阴性需氧和厌氧菌具有卓越的活性。可用于对碳青霉烯类不敏感细菌和铜绿假单胞菌生物膜感染的研究。[1-3] |
| Data Literature Source | [1]. Motsch J，et al. RESTORE-IMI 1: A Multicenter，Randomized，Double-blind Trial Comparing Efficacy and Safety of Imipenem/Relebactam vs Colistin Plus Imipenem in Patients With Imipenem-nonsusceptible Bacterial Infections. Clin Infect Dis. 2020 Apr 15;70(9):1799-1808. [2]. Hengzhuang W，et al In vivo pharmacokinetics/pharmacodynamics of colistin and imipenem in Pseudomonas aeruginosa biofilm infection. Antimicrob Agents Chemother. 2012 May;56(5):2683-90. [3]. Tally FP，et al. In vitro activity of N-formimidoyl thienamycin (MK0787). Antimicrob Agents Chemother. 1980 Oct;18(4):642-4. |
| Unit | Bottle |
| Specification | 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
A comprehensive description of the TolC effect on the antimicrobial susceptibility profile in Enterobacter bugandensis
Click to check >>Author：Li B; Zhang J; Li X
IF：4.8310
Publish_to：Front Cell Infect Microbiol
PMID：36569193
Co-Occurrence of the blaKPC-2 and Mcr-3.3 Gene in Aeromonas caviae SCAc2001 Isolated from Patients with Diarrheal Disease
Click to check >>Author：Tang L; Huang J; She J; Zhao K; Zhou Y
IF：3.9000
Publish_to：Infect Drug Resist
PMID：32547122
Manual Download
