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My CartCAS：3546-41-6
Molecular Formula：2C26H28N3·C23H14O6
Molecular Weight：1151.39
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
Qty：
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| CAS | 3546-41-6 |
| Name | Pyrvinium pamoate |
| Molecular Formula | 2C26H28N3·C23H14O6 |
| Molecular Weight | 1151.39 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 222-596-3 |
| MDL | MFCD00010090 |
| SMILES | CC1=CC(=C(N1C2=CC=CC=C2)C)C=CC3=[N+](C4=C(C=C3)C=C(C=C4)N(C)C)C.CC1=CC(=C(N1C2=CC=CC=C2)C)C=CC3=[N+](C4=C(C=C3)C=C(C=C4)N(C)C)C.C1=CC=C2C(=C1)C=C(C(=C2CC3=C(C(=CC4=CC=CC=C43)C(=O)O)[O-])[O-])C(=O)O |
| InChIKey | OOPDAHSJBRZRPH-UHFFFAOYSA-L |
| InChI | InChI=1S/2C26H28N3.C23H16O6/c2*1-19-17-21(20(2)29(19)24-9-7-6-8-10-24)11-13-23-14-12-22-18-25(27(3)4)15-16-26(22)28(23)5;24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29/h2*6-18H，1-5H3;1-10，24-25H，11H2，(H，26，27)(H，28，29)/q2*+1;/p-2 |
| PubChem CID | 54680693 |
| Target Point | Parasite |
| Passage | Anti-infection |
| Background | It is an anti-worm compound. |
| Biological Activity | Pyrvinium pamoate 是一种抗蠕虫药，可抑制 WNT 通路信号传导。[1-2] |
| Data Literature Source | [1]. Xu L，et al. WNT pathway inhibitor pyrvinium pamoate inhibits the self-renewal and metastasis of breast cancer stem cells. Int J Oncol. 2016 Mar;48(3):1175-86. [2]. Wiegering A，et al. The impact of pyrvinium pamoate on colon cancer cell viability. Int J Colorectal Dis. 2014 Oct;29(10):1189-98. [3]. Venerando A，et al. Pyrvinium pamoate does not activate protein kinase CK1，but promotes Akt/PKB down-regulation and GSK3 activation. Biochem J. 2013 May 15;452(1):131-7. [5]. Murakoshi M，et al. An anthelmintic drug，pyrvinium pamoate，thwarts fibrosis and ameliorates myocardial contractile dysfunction in a mouse model of myocardial infarction. PLoS One. 2013 Nov 4;8(11):e79374. |
| Unit | Bottle |
| Specification | 10mg 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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