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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Neuronal Signal Pathway > Ropinirole HydrochlorideCAS：91374-20-8
Molecular Formula：C16H25ClN2O
Molecular Weight：296.84
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 91374-20-8 |
| Name | Ropinirole Hydrochloride |
| Molecular Formula | C16H25ClN2O |
| Molecular Weight | 296.84 |
| Solubility | Soluble in Water/DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD01754173 |
| SMILES | CCCN(CCC)CCC1=C2CC(=O)NC2=CC=C1.Cl |
| InChIKey | XDXHAEQXIBQUEZ-UHFFFAOYSA-N |
| InChI | InChI=1S/C16H24N2O.ClH/c1-3-9-18(10-4-2)11-8-13-6-5-7-15-14(13)12-16(19)17-15;/h5-7H，3-4，8-12H2，1-2H3，(H，17，19);1H |
| PubChem CID | 68727 |
| Target Point | Dopamine Receptor |
| Passage | Neuronal Signaling;GPCR & G Protein |
| Background | It is a selective D2 receptor inhibitor and has the potential to be used in Parkinsons disease. |
| Biological Activity | Ropinirole Hydrochloride 是一种口服活性强效 D3/D2 受体激动剂，对 D2 受体的 Ki 值为 29 nM，对 hD2、hD3 和 hD4 受体的 pEC50 分别为 7.4、8.4 和 6.8，对 D1 受体没有亲和力，具有治疗帕金森病的潜力。[1-2] |
| Data Literature Source | [1]. Eden RJ，et al. Preclinical pharmacology of ropinirole (SK&F 101468-A) a novel dopamine D2 agonist. Pharmacol Biochem Behav. 1991 Jan;38(1):147-54. [2]. Mavrikaki M，et al. Ropinirole regulates emotionality and neuronal activity markers in the limbic forebrain. Int J Neuropsychopharmacol. 2014 Dec;17(12):1981-93. |
| Unit | Bottle |
| Specification | 25mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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