{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Endocrinology & Hormones > SalmeterolCAS：89365-50-4
Molecular Formula：C25H37NO4
Molecular Weight：415.57
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 89365-50-4 |
| Name | Salmeterol |
| Molecular Formula | C25H37NO4 |
| Molecular Weight | 415.57 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00867037 |
| SMILES | C1=CC=C(C=C1)CCCCOCCCCCCNCC(C2=CC(=C(C=C2)O)CO)O |
| InChIKey | GIIZNNXWQWCKIB-UHFFFAOYSA-N |
| InChI | InChI=1S/C25H37NO4/c27-20-23-18-22(13-14-24(23)28)25(29)19-26-15-7-1-2-8-16-30-17-9-6-12-21-10-4-3-5-11-21/h3-5，10-11，13-14，18，25-29H，1-2，6-9，12，15-17，19-20H2 |
| PubChem CID | 5152 |
| Target Point | Adrenergic Receptor |
| Passage | Endocrinology & Hormones;GPCR & G Protein；Neuronal Signaling |
| Background | It is a potent and selective beta-2 adrenergic receptor agonist. |
| Biological Activity | Salmeterol 是一种强效、选择性的人类 β2 肾上腺素受体激动剂。能有效刺激 cAMP 的积累，在表达人 β2、β1 和 β3 肾上腺素受体的 CHO 细胞中，pEC50s 分别为 9.6、6.1 和 5.9。[1] |
| Data Literature Source | [1]. Procopiou PA，et al. The discovery of long-acting saligenin β adrenergic receptor agonists incorporating a urea group. Bioorg Med Chem. 2011 Oct 15;19(20):6026-32. [2]. Johnson M. Effects of beta2-agonists on resident and infiltrating inflammatory cells. J Allergy Clin Immunol. 2002 Dec;110(6 Suppl):S282-90. [3]. Wang Z，Wang C，Yang X. Efficacy of salmeterol and formoterol combination treatment in mice with chronic obstructive pulmonary disease. Exp Ther Med. 2018 Feb;15(2):1538-1545. |
| Unit | Bottle |
| Specification | 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
