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My CartCAS：63-74-1
Molecular Formula：C6H8N2O2S
Molecular Weight：172.2
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 63-74-1 |
| Name | Sulfanilamide |
| Molecular Formula | C6H8N2O2S |
| Molecular Weight | 172.2 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 200-563-4 |
| MDL | MFCD00007939 |
| SMILES | C1=CC(=CC=C1N)S(=O)(=O)N |
| InChIKey | FDDDEECHVMSUSB-UHFFFAOYSA-N |
| InChI | InChI=1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8，9)10/h1-4H，7H2，(H2，8，9，10) |
| PubChem CID | 5333 |
| Target Point | Bacterial |
| Passage | Anti-infection |
| Background | Sulfanilamide is a competing inhibitor of the synthesis of dihydrotrexate in bacterial enzymes. |
| Biological Activity | Sulfanilamide 是细菌酶中二氢喋呤合成的适度竞争性抑制剂，是一种有效的口服磺胺类抗生素，是磺胺甲恶唑生物降解的主要中间体，可预防卡氏肺孢子虫和肺炎病菌感染。[1-4] |
| Data Literature Source | [1]. Liao X，et al. Antibiotic sulfanilamide biodegradation by acclimated microbial populations. Appl Microbiol Biotechnol. 2016 Mar;100(5):2439-47. [2]. Pade skaia EN，et al. Sravnitel'naia aktivnost' depo-sul'fanilamidov pri éksperimental'no infektsii myshe ，vyzvanno K1. pneumoniae [Comparative activity of depot sulfanilamides in experimental infection in mice caused by K1. pneumoniae]. Antibiotiki. 1980 Mar;25(3):193-8. [3]. Hughes WT，et al. Monodrug efficacies of sulfonamides in prophylaxis for Pneumocystis carinii pneumonia. Antimicrob Agents Chemother. 1996 Apr;40(4):962-5. [4]. McCullough JL，et al. Inhibition of dihydropteroate synthetase from Escherichia coli by sulfones and sulfonamides. Antimicrob Agents Chemother. 1973 Jun;3(6):665-9. |
| Unit | Bottle |
| Specification | 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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