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My CartCAS：139110-80-8
Molecular Formula：C12H20N4O7
Molecular Weight：332.31
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 139110-80-8 |
| Name | Zanamivir |
| Molecular Formula | C12H20N4O7 |
| Molecular Weight | 332.31 |
| Solubility | Soluble in Water(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00866966 |
| SMILES | CC(=O)N[C@@H]1[C@H](C=C(O[C@H]1[C@@H]([C@@H](CO)O)O)C(=O)O)N=C(N)N |
| InChIKey | ARAIBEBZBOPLMB-UFGQHTETSA-N |
| InChI | InChI=1S/C12H20N4O7/c1-4(18)15-8-5(16-12(13)14)2-7(11(21)22)23-10(8)9(20)6(19)3-17/h2，5-6，8-10，17，19-20H，3H2，1H3，(H，15，18)(H，21，22)(H4，13，14，16)/t5-，6+，8+，9+，10+/m0/s1 |
| PubChem CID | 60855 |
| Target Point | Influenza Virus |
| Passage | Anti-infection |
| Background | Zanamivir is a neuraminidase inhibitor of influenza virus with anti-influenza activity. |
| Biological Activity | Zanamivir 是流感病毒的神经氨酸酶抑制剂，对于流感病毒 A 和 B 的IC50值分别为 0.95 nM 和 2.7 nM。[1] |
| IC50 | Influenza A: 0.95nM(IC50);Influenza B: 2.7nM(IC50)[1] |
| Data Literature Source | [1]. Gubareva LV，et al. Comparison of the activities of zanamivir，oseltamivir，and RWJ-270201 against clinical isolates of influenza virus and neuraminidase inhibitor-resistant variants. Antimicrob Agents Chemother. 2001 Dec;45(12):3403-8. [2]. Gubareva LV，et al. Characterization of influenza A/HongKong/156/97 (H5N1) virus in a mouse model and protective effect of zanamivir on H5N1 infection in mice. J Infect Dis. 1998 Dec;178(6):1592-6. [3]. Wang MZ，et al. Mechanism by which mutations at his274 alter sensitivity of influenza a virus n1 neuraminidase to oseltamivir carboxylate and zanamivir. Antimicrob Agents Chemother. 2002 Dec;46(12):3809-16. [4]. Greengard O，et al. The anti-influenza virus agent 4-GU-DANA (zanamivir) inhibits cell fusion mediated by human parainfluenza virus and influenza virus HA. J Virol. 2000 Dec;74(23):11108-14. |
| Unit | Bottle |
| Specification | 5mg 10mg 20mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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