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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Endocrinology & Hormones > Betaxolol HydrochlorideCAS：63659-19-8
Molecular Formula：C18H30ClNO3
Molecular Weight：343.89
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 63659-19-8 |
| Name | Betaxolol Hydrochloride |
| Molecular Formula | C18H30ClNO3 |
| Molecular Weight | 343.89 |
| Solubility | Soluble in Water/DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 264-384-3 |
| MDL | MFCD00242959 |
| SMILES | CC(C)NCC(COC1=CC=C(C=C1)CCOCC2CC2)O.Cl |
| InChIKey | CHDPSNLJFOQTRK-UHFFFAOYSA-N |
| InChI | InChI=1S/C18H29NO3.ClH/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16;/h5-8，14，16-17，19-20H，3-4，9-13H2，1-2H3;1H |
| PubChem CID | 107952 |
| Target Point | Adrenergic Receptor |
| Passage | Endocrinology & Hormones;GPCR & G Protein；Neuronal Signaling |
| Background | It is a beta1 adrenergic receptor blocker that can be used in studies of high blood pressure and glaucoma. |
| Biological Activity | Betaxolol Hydrochloride 是一种β1肾上腺素受体阻断剂，IC50是6 Μm，可用于高血压和青光眼的研究。[1-3] |
| IC50 | β1-adrenergic receptor: 6μM(IC50)[1] |
| Data Literature Source | [1]. Tang LQ，et al. Effect of beta-adrenergic agents on intracellular potential of rabbit ciliary epithelium. Curr Eye Res. 1998 Jan;17(1):24-30. [2]. Rudoy CA，et al. Betaxolol，a selective beta(1)-adrenergic receptor antagonist，diminishes anxiety-like behavior during early withdrawal from chronic cocaine administration in rats. Prog Neuropsychopharmacol Biol Psychiatry. 2007 Jun 30;31(5):1119-29. [3]. Lesar TS. Comparison of ophthalmic beta-blocking agents. Clin Pharm. 1987 Jun;6(6):451-63. |
| Unit | Bottle |
| Specification | 10mg 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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