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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Neuronal Signal Pathway > Citalopram HydrobromideCAS：59729-32-7
Molecular Formula：C20H22BrFN2O
Molecular Weight：405.3
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 59729-32-7 |
| Name | Citalopram Hydrobromide |
| Molecular Formula | C20H22BrFN2O |
| Molecular Weight | 405.3 |
| Solubility | Soluble in Water/DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 261-890-6 |
| MDL | MFCD02101306 |
| SMILES | CN(C)CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F.Br |
| InChIKey | WIHMBLDNRMIGDW-UHFFFAOYSA-N |
| InChI | InChI=1S/C20H21FN2O.BrH/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20;/h4-9，12H，3，10-11，14H2，1-2H3;1H |
| PubChem CID | 77995 |
| Target Point | Serotonin Transporter |
| Passage | Neuronal Signaling |
| Background | It is a selective serotonin reuptake inhibitor (SSRI) that inhibits 5-HT uptake into the synaptosomes. |
| Biological Activity | Citalopram Hydrobromide 是一种新的双环酞烷衍生物，是神经元血清素（5-HT）摄取的强效抑制剂，IC50 为 1.8 nM。可抑制兔血小板对 5-HT 的摄取，IC50 为 14 nM。抗抑郁作用。[1] |
| Data Literature Source | [1]. Hyttel J. Citalopram--pharmacological profile of a specific serotonin uptake inhibitor with antidepressant activity. Prog Neuropsychopharmacol Biol Psychiatry. 1982;6(3):277-95. [2]. Sakka L，et al. Assessment of citalopram and escitalopram on neuroblastoma cell lines. Cell toxicity and gene modulation. Oncotarget. 2017 Jun 27;8(26):42789-42807. [3]. Pollier F，et al. Serotonin reuptake inhibition by citalopram in rat strains differing for their emotionality. Neuropsychopharmacology. 2000 Jan;22(1):64-76. |
| Unit | Bottle |
| Specification | 10mg 25mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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