{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Membrane Transporter & Ion Channel > Desipramine HydrochlorideCAS：58-28-6
Molecular Formula：C18H23ClN2
Molecular Weight：302.84
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 58-28-6 |
| Name | Desipramine Hydrochloride |
| Molecular Formula | C18H23ClN2 |
| Molecular Weight | 302.84 |
| Solubility | Soluble in Water/DMSO ≥5mg/mL |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 200-373-1 |
| SMILES | CNCCCN1C2=CC=CC=C2CCC3=CC=CC=C31.Cl |
| InChIKey | XAEWZDYWZHIUCT-UHFFFAOYSA-N |
| InChI | InChI=1S/C18H22N2.ClH/c1-19-13-6-14-20-17-9-4-2-7-15(17)11-12-16-8-3-5-10-18(16)20;/h2-5，7-10，19H，6，11-14H2，1H3;1H |
| PubChem CID | 65327 |
| Target Point | NET;SERT;DAT |
| Passage | Membrane Transporter&Ion Channel;Neuronal Signaling；GPCR & G Protein |
| Background | It is an inhibitor of norepinephrine transporter (NET), serotonin transporter (SERT) and dopamine transporter (DAT). |
| Biological Activity | Desipramine hydrochloride 是去甲肾上腺素转运蛋白 (NET)，5-羟色胺转运体 (SERT) 和多巴胺转运 (DAT) 的抑制剂，其 Ki 值分别为 4，61 和 78，720 nM。[1-2] |
| Data Literature Source | [1]. Torres GE，et al. Plasma membrane monoamine transporters: structure，regulation and function. Nat Rev Neurosci. 2003 Jan;4(1):13-25. [2]. Zhao Z，et al. Norepinephrine transporter regulation mediates the long-term behavioral effects of the antidepressant desipramine. Neuropsychopharmacology. 2008 Dec;33(13):3190-200. |
| Unit | Bottle |
| Specification | 50mg 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
