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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Neuronal Signal Pathway > Dihydroergotamine MesylateCAS：6190-39-2
Molecular Formula：C34H41N5O8S
Molecular Weight：679.78
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 6190-39-2 |
| Name | Dihydroergotamine Mesylate |
| Molecular Formula | C34H41N5O8S |
| Molecular Weight | 679.78 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 228-235-6 |
| MDL | MFCD00058615 |
| SMILES | CC1(C(=O)N2C(C(=O)N3CCCC3C2(O1)O)CC4=CC=CC=C4)NC(=O)C5CC6C(CC7=CNC8=CC=CC6=C78)N(C5)C.CS(=O)(=O)O |
| InChIKey | ADYPXRFPBQGGAH-UMYZUSPBSA-N |
| InChI | InChI=1S/C33H37N5O5.CH4O3S/c1-32(35-29(39)21-15-23-22-10-6-11-24-28(22)20(17-34-24)16-25(23)36(2)18-21)31(41)38-26(14-19-8-4-3-5-9-19)30(40)37-13-7-12-27(37)33(38，42)43-32;1-5(2，3)4/h3-6，8-11，17，21，23，25-27，34，42H，7，12-16，18H2，1-2H3，(H，35，39);1H3，(H，2，3，4)/t21-，23-，25-，26+，27+，32-，33+;/m1./s1 |
| PubChem CID | 71171 |
| Target Point | 5-HT Receptor |
| Passage | Neuronal Signaling；GPCR & G Protein |
| Background | The Dihydroergotamine is an agonist of the 5-HT2B and 5-HT2C sensors and is applicable to migraine orientation studies. |
| Biological Activity | The pharmaceutical compound， dihydroergotamine (DHE) is dispensed to prevent and reduce the occurrence of migraine attacks. The prophylactic effect of this drug is believed to be caused through blockade and/or activation of numerous receptors including serotonin (5-HT) receptors of the 5-HT2 subtype. [1] |
| Data Literature Source | [1]. Schaerlinger B，Hickel P，Etienne N，Guesnier L，Maroteaux L. Agonist actions of dihydroergotamine at 5-HT2B and 5-HT2C receptors and their possible relevance to antimigraine efficacy. Br J Pharmacol. 2003 Sep;140(2):277-84. |
| Unit | Bottle |
| Specification | 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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