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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Endocrinology & Hormones > Naphazoline HydrochlorideCAS：550-99-2
Molecular Formula：C14H15ClN2
Molecular Weight：246.74
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 550-99-2 |
| Name | Naphazoline Hydrochloride |
| Molecular Formula | C14H15ClN2 |
| Molecular Weight | 246.74 |
| Solubility | Soluble in Water/DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 208-989-2 |
| MDL | MFCD00012554 |
| SMILES | C1CN=C(N1)CC2=CC=CC3=CC=CC=C32.Cl |
| InChIKey | DJDFFEBSKJCGHC-UHFFFAOYSA-N |
| InChI | InChI=1S/C14H14N2.ClH/c1-2-7-13-11(4-1)5-3-6-12(13)10-14-15-8-9-16-14;/h1-7H，8-10H2，(H，15，16);1H |
| PubChem CID | 11079 |
| Target Point | Adrenergic Receptor |
| Passage | Endocrinology & Hormones;GPCR & G Protein；Neuronal Signaling |
| Background | It is an effective alpha-Adrenergic receptor agonist. |
| Biological Activity | Naphazoline Hydrochloride 是一种α-肾上腺素能受体激动剂，盐酸萘甲唑啉可降低血管高渗透性，促进血管收缩，可降低炎症因子（TNF-α、IL-1β 和 IL-6）、细胞因子（IFN-γ 和 IL-4）、IgE、GMCSF 和 NGF 的水平。[1-2] |
| Data Literature Source | [1]. Quan L，et al. Treatment with olopatadine and naphazoline hydrochloride reduces allergic conjunctivitis in mice through alterations in inflammation，NGF and VEGF. Mol Med Rep. 2016 Apr;13(4):3319-25. [2]. Yamaguchi I，et al. Central and peripheral adrenergic mechanisms regulating gastric secretion in the rat. J Pharmacol Exp Ther. 1977 Oct;203(1):125-31. |
| Unit | Bottle |
| Specification | 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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