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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Neuronal Signal Pathway > Pilocarpine HydrochlorideCAS：54-71-7
Molecular Formula：C11H17ClN2O2
Molecular Weight：244.72
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 54-71-7 |
| Name | Pilocarpine Hydrochloride |
| Molecular Formula | C11H17ClN2O2 |
| Molecular Weight | 244.72 |
| Solubility | Soluble in Water/DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 200-212-5 |
| MDL | MFCD00012722 |
| SMILES | CCC1C(COC1=O)CC2=CN=CN2C.Cl |
| InChIKey | RNAICSBVACLLGM-GNAZCLTHSA-N |
| InChI | InChI=1S/C11H16N2O2.ClH/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2;/h5，7-8，10H，3-4，6H2，1-2H3;1H/t8-，10-;/m0./s1 |
| PubChem CID | 5909 |
| Target Point | mAChR |
| Passage | Neuronal Signaling;GPCR & G Protein |
| Background | It is an effective M3 muscarinic receptor agonist. |
| Biological Activity | Pilocarpine Hydrochloride 是一种强效的 M3 毒蕈碱乙酰胆碱受体激动剂。[1-4] |
| Data Literature Source | [1]. Matsuzaki K，et al. Daily voluntary exercise enhances pilocarpine-induced saliva secretion and aquaporin 1 expression in rat submandibular glands. FEBS Open Bio. 2017 Dec 7;8(1):85-93. [2]. Tonta MA，et al. Pilocarpine-induced relaxation of rat tail artery by a non-cholinergic mechanism and in the absence of an intact endothelium. Br J Pharmacol. 1994 Jun;112(2):525-32. [3]. Yuan XL，et al. Cytotoxicity of pilocarpine to human corneal stromal cells and its underlying cytotoxic mechanisms. Int J Ophthalmol. 2016 Apr 18;9(4):505-11. [4]. Wang RF，et al. Post-treatment with the GLP-1 analogue liraglutide alleviate chronic inflammation and mitochondrial stress induced by Status epilepticus. Epilepsy Res. 2018 May;142:45-52. |
| Unit | Bottle |
| Specification | 50mg 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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