{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Neuronal Signal Pathway > PomaglumetadCAS：635318-11-5
Molecular Formula：C7H9NO6S
Molecular Weight：235.21
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
Qty：
Size：
| CAS | 635318-11-5 |
| Name | Pomaglumetad |
| Molecular Formula | C7H9NO6S |
| Molecular Weight | 235.21 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | C1C(C2C(C2S1(=O)=O)C(=O)O)(C(=O)O)N |
| InChIKey | AVDUGNCTZRCAHH-MDASVERJSA-N |
| InChI | InChI=1S/C7H9NO6S/c8-7(6(11)12)1-15(13，14)4-2(3(4)7)5(9)10/h2-4H，1，8H2，(H，9，10)(H，11，12)/t2-，3-，4+，7+/m1/s1 |
| PubChem CID | 9834591 |
| Target Point | mGluR |
| Passage | Neuronal Signaling;GPCR & G Protein |
| Background | It is an effective and selective mGluR2 and mGluR3 agonist, which can be used in antipsychotic and antianxiety related studies. |
| Biological Activity | Pomaglumetad 是一种强效、有选择性和口服活性的 mGluR2 和 mGluR3 激动剂，对重组人 mGluR2 和 mGluR3 的 Kis 分别为 149 nM 和 92 nM，具有抗精神病和抗焦虑作用。[1] |
| Data Literature Source | [1]. Rorick-Kehn LM，et al. Pharmacological and pharmacokinetic properties of a structurally novel，potent，and selective metabotropic glutamate 2/3 receptor agonist: in vitro characterization of agonist (-)-(1R，4S，5S，6S)-4-amino-2-sulfonylbicyclo[3.1.0]-hexane-4，6-dicarboxylic acid (LY404039). J Pharmacol Exp Ther. 2007 Apr;321(1):308-17. [2]. Rorick-Kehn LM，et al. In vivo pharmacological characterization of the structurally novel，potent，selective mGlu2/3 receptor agonist LY404039 in animal models of psychiatric disorders. Psychopharmacology (Berl). 2007 Jul;193(1):121-36. |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
