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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Neuronal Signal Pathway > Vanoxerine DihydrochlorideCAS：67469-78-7
Molecular Formula：C28H34Cl2F2N2O
Molecular Weight：523.49
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 67469-78-7 |
| Name | Vanoxerine Dihydrochloride |
| Molecular Formula | C28H34Cl2F2N2O |
| Molecular Weight | 523.49 |
| Solubility | Soluble in Water/DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00055193 |
| SMILES | C1CN(CCN1CCCC2=CC=CC=C2)CCOC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F.Cl.Cl |
| InChIKey | MIBSKSYCRFWIRU-UHFFFAOYSA-N |
| InChI | InChI=1S/C28H32F2N2O.2ClH/c29-26-12-8-24(9-13-26)28(25-10-14-27(30)15-11-25)33-22-21-32-19-17-31(18-20-32)16-4-7-23-5-2-1-3-6-23;;/h1-3，5-6，8-15，28H，4，7，16-22H2;2*1H |
| PubChem CID | 104920 |
| Target Point | Dopamine Transporter |
| Passage | Neuronal Signaling;Membrane Transporter&Ion Channel |
| Background | It is a competitive, highly selective inhibitor of dopamine reuptake that binds to a target on the dopamine transporter (DAT). |
| Biological Activity | Vanoxerine Dihydrochloride 是一种竞争性、强效、高选择性多巴胺再摄取抑制剂（Ki=1 nM），可与多巴胺转运体（DAT）上的靶点结合。[1-2] |
| Data Literature Source | [1]. Hirate K，et al. Characteristics of the ambulation-increasing effect of GBR-12909，a selective dopamine uptake inhibitor，in mice. Jpn J Pharmacol. 1991 Apr;55(4):501-11. [2]. Andersen PH. The dopamine inhibitor GBR 12909: selectivity and molecular mechanism of action. Eur J Pharmacol. 1989 Aug 3;166(3):493-504. |
| Unit | Bottle |
| Specification | 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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