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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cytoskeleton > Cytochalasin ECAS：36011-19-5
Molecular Formula：C28H33NO7
Molecular Weight：495.56
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
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| CAS | 36011-19-5 |
| Name | Cytochalasin E |
| Molecular Formula | C28H33NO7 |
| Molecular Weight | 495.56 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 252-835-7 |
| MDL | MFCD00005178 |
| SMILES | CC1CC=CC2C3C(O3)(C(C4C2(C(=O)NC4CC5=CC=CC=C5)OC(=O)OC=CC(C1=O)(C)O)C)C |
| InChIKey | LAJXCUNOQSHRJO-ZYGJITOWSA-N |
| InChI | InChI=1S/C28H33NO7/c1-16-9-8-12-19-23-27(4，35-23)17(2)21-20(15-18-10-6-5-7-11-18)29-24(31)28(19，21)36-25(32)34-14-13-26(3，33)22(16)30/h5-8，10-14，16-17，19-21，23，33H，9，15H2，1-4H3，(H，29，31)/b12-8+，14-13+/t16-，17-，19-，20-，21-，23-，26+，27+，28+/m0/s1 |
| PubChem CID | 5458385 |
| Target Point | Actin |
| Passage | Cytoskeleton |
| Background | It is an effective actin depolymerization agent that can bind and cover the barb end of actin filaments to prevent actin elongation. |
| Biological Activity | Cytochalasin E 是一种强效肌动蛋白解聚剂，也是一种含有环氧化物的曲霉衍生真菌代谢物，还能抑制血管生成和肿瘤生长。[1-2] |
| Data Literature Source | [1]. Udagawa T，et al. Cytochalasin E，an epoxide containing Aspergillus-derived fungal metabolite，inhibits angiogenesis and tumor growth. J Pharmacol Exp Ther. 2000 Aug;294(2):421-7. [2]. Takanezawa Y，et al. Variation in the activity of distinct cytochalasins as autophagy inhibitiors in human lung A549 cells. Biochem Biophys Res Commun. 2017 Dec 16;494(3-4):641-647. |
| Unit | Bottle |
| Specification | 1mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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