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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Endocrinology & Hormones > Idazoxan HydrochlorideCAS：79944-56-2
Molecular Formula：C11H13ClN2O2
Molecular Weight：240.69
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 79944-56-2 |
| Name | Idazoxan Hydrochloride |
| Molecular Formula | C11H13ClN2O2 |
| Molecular Weight | 240.69 |
| Solubility | Soluble in Water/DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00069293 |
| SMILES | C1CN=C(N1)C2COC3=CC=CC=C3O2.Cl |
| InChIKey | MYUBYOVCLMEAOH-UHFFFAOYSA-N |
| InChI | InChI=1S/C11H12N2O2.ClH/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11;/h1-4，10H，5-7H2，(H，12，13);1H |
| PubChem CID | 154494 |
| Target Point | Adrenergic Receptor;Imidazoline Receptor |
| Passage | Endocrinology & Hormones;GPCR & G Protein;Neuronal Signaling |
| Background | It is an alpha2-adrenergic receptor antagonist and an imidazoline receptor (IRs) antagonist. |
| Biological Activity | Idazoxan Hydrochloride 是一种α2-肾上腺素受体拮抗剂，也是一种咪唑啉受体（IRs）拮抗剂，可竞争性拮抗咪唑啉类药物（IMs）的中枢诱导降压作用，还能改善帕金森病的症状。[1-2] |
| Data Literature Source | [1]. Jackson HC，et al. The effects of idazoxan and other alpha 2-adrenoceptor antagonists on food and water intake in the rat. Br J Pharmacol. 1991 Sep;104(1):258-62. [2]. Bousquet P，et al. Participation of imidazoline receptors and alpha(2-)-adrenoceptors in the central hypotensive effects of imidazoline-like drugs. Ann N Y Acad Sci. 1999 Jun 21;881:272-8. |
| Unit | Bottle |
| Specification | 2mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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