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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Neuronal Signal Pathway > BiperidenCAS：514-65-8
Molecular Formula：C21H29NO
Molecular Weight：311.46
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
Qty：
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| CAS | 514-65-8 |
| Name | Biperiden |
| Molecular Formula | C21H29NO |
| Molecular Weight | 311.46 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 208-184-6 |
| MDL | MFCD05662335 |
| SMILES | C1CCN(CC1)CCC(C2CC3CC2C=C3)(C4=CC=CC=C4)O |
| InChIKey | YSXKPIUOCJLQIE-UHFFFAOYSA-N |
| InChI | InChI=1S/C21H29NO/c23-21(19-7-3-1-4-8-19，11-14-22-12-5-2-6-13-22)20-16-17-9-10-18(20)15-17/h1，3-4，7-10，17-18，20，23H，2，5-6，11-16H2 |
| PubChem CID | 2381 |
| Target Point | mAChR |
| Passage | Neuronal Signaling;GPCR & G Protein |
| Background | It is a non-selective muscarinic receptor antagonist that can competitively bind to M1 muscarinic receptor, thereby inhibiting acetylcholine and enhancing dopamine signaling in the central nervous system. |
| Biological Activity | Biperiden 是一种非选择性毒蕈碱受体拮抗剂，可竞争性地与 M1 毒蕈碱受体结合，抑制乙酰胆碱并增强中枢神经系统中的多巴胺信号传导，具有研究帕金森病等精神疾病的潜力。[1-2] |
| Data Literature Source | [1]. Konczalla L，et al. Biperiden and mepazine effectively inhibit MALT1 activity and tumor growth in pancreatic cancer. Int J Cancer. 2020 Mar 15;146(6):1618-1630. [2]. Bittencourt S，et al. Modification of the natural progression of epileptogenesis by means of biperiden in the pilocarpine model of epilepsy. Epilepsy Res. 2017 Dec;138:88-97. [3]. Pehl C，et al. Effects of two anticholinergic drugs，trospium chloride and biperiden，on motility and evoked potentials of the oesophagus. Aliment Pharmacol Ther. 1998 Oct;12(10):979-84. |
| Unit | Bottle |
| Specification | 1mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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