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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Neuronal Signal Pathway > SynuClean-DCAS：685121-45-3
Molecular Formula：C13H5F3N4O5
Molecular Weight：354.2
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to yellow Solid
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| CAS | 685121-45-3 |
| Name | SynuClean-D |
| Molecular Formula | C13H5F3N4O5 |
| Molecular Weight | 354.2 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | C1=CC(=CC(=C1)[N+](=O)[O-])C2=C(C(=C(C(=O)N2)C#N)C(F)(F)F)[N+](=O)[O-] |
| InChIKey | OJRLTEJFYMZKQB-UHFFFAOYSA-N |
| InChI | InChI=1S/C13H5F3N4O5/c14-13(15，16)9-8(5-17)12(21)18-10(11(9)20(24)25)6-2-1-3-7(4-6)19(22)23/h1-4H，(H，18，21) |
| PubChem CID | 2726228 |
| Target Point | α-synuclein |
| Passage | Neuronal Signaling |
| Background | It is an inhibitor of alpha-synuclein aggregation, which can destroy mature amyloid fibrils, prevent fibrils from proliferating, and eliminate the degeneration of dopaminergic neurons in animal models of Parkinsons disease. |
| Biological Activity | SynuClean-D 能够抑制α-突触核蛋白聚集，被用于帕金森病的治疗。[1] |
| Data Literature Source | [1]. Pujols J，et al. Small molecule inhibits α-synuclein aggregation，disrupts amyloid fibrils，and prevents degeneration of dopaminergic neurons. Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10481-10486. |
| Unit | Bottle |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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