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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Neuronal Signal Pathway > Rivastigmine TartrateCAS：129101-54-8
Molecular Formula：C18H28N2O8
Molecular Weight：400.42
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 129101-54-8 |
| Name | Rivastigmine Tartrate |
| Molecular Formula | C18H28N2O8 |
| Molecular Weight | 400.42 |
| Solubility | Soluble in Water/DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD03700731 |
| SMILES | CCN(C)C(=O)OC1=CC=CC(=C1)[C@H](C)N(C)C.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O |
| InChIKey | GWHQHAUAXRMMOT-MBANBULQSA-N |
| InChI | InChI=1S/C14H22N2O2.C4H6O6/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4;5-1(3(7)8)2(6)4(9)10/h7-11H，6H2，1-5H3;1-2，5-6H，(H，7，8)(H，9，10)/t11-;1-，2-/m01/s1 |
| PubChem CID | 6918078 |
| Target Point | AChE;BChE |
| Passage | Neuronal Signaling |
| Background | It is a potent cholinesterase (ChE) inhibitor that inhibits butyryl cholinesterase (BChE) and acetylcholinesterase (AChE). |
| Biological Activity | Rivastigmine Tartrate 是一种口服活性强效胆碱酯酶（ChE）抑制剂，可抑制丁酰胆碱酯酶（BChE）和乙酰胆碱酯酶（AChE），其 IC50 值分别为 0.037 μM 和 4.15 μM，可用于研究阿尔茨海默型痴呆和帕金森病所致痴呆。 |
| IC50 | BChE: 0.037μM(IC50);AChE: 4.15μM(IC50)[1] |
| Data Literature Source | [1]. Yu QS，et al. Anticholinesterase activity of compounds related to geneserine tautomers. N-Oxides and 1，2-oxazines. J Med Chem. 2002 Aug 15;45(17):3684-91. [2]. Shifrin H，et al. Rivastigmine alleviates experimentally induced colitis in mice and rats by acting at central and peripheral sites to modulate immune responses. PLoS One. 2013;8(2):e57668. [3]. Abdel-Aal RA，et al. Rivastigmine reverses aluminum-induced behavioral changes in rats. Eur J Pharmacol. 2011 Jun 1;659(2-3):169-76. |
| Unit | Bottle |
| Specification | 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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