Your Position: Home > Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Neuronal Signal Pathway > Rivastigmine

Rivastigmine

Manual Download

Cat.No：IR1310 Solarbio

CAS：123441-03-2

Molecular Formula：C₁₄H₂₂N₂O₂

Molecular Weight：250.34

Storage：Store at 2-8℃，2 years

Purity：≥98%

Appearance：Liquid

Qty：

Size：

Add to cart

Product Information Experimental Images Related Products Related Paper Technical Q&A

Product Information

CAS	123441-03-2
Name	Rivastigmine
Molecular Formula	C₁₄H₂₂N₂O₂
Molecular Weight	250.34
Solubility	Soluble in DMSO
Purity	≥98%
Appearance	Liquid
Storage	Store at 2-8℃，2 years
Density	1.038g/mL
MDL	MFCD00871496
SMILES	CCN(C)C(=O)OC1=CC=CC(=C1)[C@H](C)N(C)C
InChIKey	XSVMFMHYUFZWBK-NSHDSACASA-N
InChI	InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H，6H2，1-5H3/t11-/m0/s1
PubChem CID	77991
Target Point	AChE;BChE
Passage	Neuronal Signaling
Background	It is a potent cholinesterase (ChE) inhibitor that inhibits butyryl cholinesterase (BChE) and acetylcholinesterase (AChE).
Biological Activity	Rivastigmine 是一种口服活性胆碱酯酶（ChE）抑制剂，可抑制丁酰胆碱酯酶（BChE）和乙酰胆碱酯酶（AChE），其 IC50 值分别为 0.037 μM 和 4.15 μM。可穿过血脑屏障（BBB），可用于研究阿尔茨海默型和帕金森病引起的痴呆。[1-3]
IC50	BChE: 0.037μM(IC50);AChE: 4.15μM(IC50)[1]
Data Literature Source	[1]. Yu QS，et al. Anticholinesterase activity of compounds related to geneserine tautomers. N-Oxides and 1，2-oxazines. J Med Chem. 2002 Aug 15;45(17):3684-91. [2]. Shifrin H，et al. Rivastigmine alleviates experimentally induced colitis in mice and rats by acting at central and peripheral sites to modulate immune responses. PLoS One. 2013;8(2):e57668. [3]. Abdel-Aal RA，et al. Rivastigmine reverses aluminum-induced behavioral changes in rats. Eur J Pharmacol. 2011 Jun 1;659(2-3):169-76.
Unit	Bottle
Specification	50mg 100mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

Note：

1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.

2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.

3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.

Experimental Images

Technical Q&A

Q&A （Total 0 User Q&A）

There is not question and answer now, come and send an inquiry please.

My question

Rank：

My question：

Identifying code：
captcha