{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Membrane Transporter & Ion Channel > CFM-2CAS：178616-26-7
Molecular Formula：C17H17N3O3
Molecular Weight：311.34
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
Qty：
Size：
| CAS | 178616-26-7 |
| Name | CFM-2 |
| Molecular Formula | C17H17N3O3 |
| Molecular Weight | 311.34 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | COC1=C(C=C2C(=C1)CC(=O)NN=C2C3=CC=C(C=C3)N)OC |
| InChIKey | MJKADKZSYQWGLL-UHFFFAOYSA-N |
| InChI | InChI=1S/C17H17N3O3/c1-22-14-7-11-8-16(21)19-20-17(13(11)9-15(14)23-2)10-3-5-12(18)6-4-10/h3-7，9H，8，18H2，1-2H3，(H，19，21) |
| PubChem CID | 4377504 |
| Target Point | AMPAR |
| Passage | Membrane Transporter&Ion Channel;Neuronal Signaling |
| Background | CFM-2 is a non-competitive inhibitor of choice for AMPAR. |
| Biological Activity | CFM-2 是一直能够选择性福 AMPA 受体拮抗剂，在癫痫发作模型中具有抗惊厥活性。[1-3] |
| Data Literature Source | [1]. De Sarro G，et al. Effects of some AMPA receptor antagonists on the development of tolerance in epilepsy-prone rats and in pentylenetetrazole kindled rats. Eur J Pharmacol. 1999 Mar 5;368(2-3):149-59. [2]. Rizzo M，et al. Determination of new 2，3-benzodiazepines in rat plasma using high-performance liquid chromatography with ultraviolet detection. J Chromatogr B Biomed Sci Appl. 1999 Aug 20;731(2):207-15. [3]. Rizzo M，et al. Determination of new 2，3-benzodiazepines in rat plasma using high-performance liquid chromatography with ultraviolet detection. J Chromatogr B Biomed Sci Appl. 1999 Aug 20;731(2):207-15. |
| Unit | Bottle |
| Specification | 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
