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My CartCAS：869572-92-9
Molecular Formula：C19H15F3N2O3
Molecular Weight：376.33
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥90%
Appearance：Solid
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| CAS | 869572-92-9 |
| Name | Tecovirimat |
| Molecular Formula | C19H15F3N2O3 |
| Molecular Weight | 376.33 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥90% |
| Appearance | Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | C1C2C1C3C=CC2C4C3C(=O)N(C4=O)NC(=O)C5=CC=C(C=C5)C(F)(F)F |
| InChIKey | CSKDFZIMJXRJGH-VWLPUNTISA-N |
| InChI | InChI=1S/C19H15F3N2O3/c20-19(21，22)9-3-1-8(2-4-9)16(25)23-24-17(26)14-10-5-6-11(13-7-12(10)13)15(14)18(24)27/h1-6，10-15H，7H2，(H，23，25)/t10-，11+，12+，13-，14-，15+ |
| PubChem CID | 16124688 |
| Target Point | Antiviral |
| Passage | Anti-infection |
| Background | It is an Antiviral compound that can inhibit the release of orthopoxviruses by targeting p37 protein orthologs, and can be used in related studies to treat smallpox infection. |
| Biological Activity | Tecovirimat 是一种口服生物活性抗痘病毒化合物，对多种正痘病毒具有强效和选择性活性，EC50 约为 10 nM。[1-2] |
| Data Literature Source | [1]. Yang G，et al. An orally bioavailable antipoxvirus compound (ST-246) inhibits extracellular virus formation and protects mice from lethal orthopoxvirus Challenge. J Virol. 2005 Oct;79(20):13139-49. [2]. Quenelle DC，et al. Efficacy of delayed treatment with ST-246 given orally against systemic orthopoxvirus infections in mice. Antimicrob Agents Chemother. 2007 Feb;51(2):689-95. |
| Unit | Bottle |
| Specification | 1mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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