{{cart_num}}
My Cart> Antibodies > Primary Antibodies > Anti-Phospho-JNK1-T183/Y185+JNK2-T183/Y185+JNK3-T221/Y223 Monoclonal AntibodyReactivity：Human,Mouse,Rat
Application：IF,IHC,WB
Clone Type：Monoclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：5599/5601/5602
Host：Rabbit
Qty：
Size：
| Name | Anti-Phospho-JNK1-T183/Y185+JNK2-T183/Y185+JNK3-T221/Y223 Monoclonal Antibody |
| Host | Rabbit |
| Clone Type | Monoclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | WB 1:1000-2100. |
| Target | Phospho-JNK1-T183/Y185 + JNK2-T183/Y185+ JNK3-T221/Y223 |
| Background | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016] |
| Swiss Prot | P45983/P45984/P53779 |
| Gene ID | 5599/5601/5602 |
| Subcellular Location | Cytoplasm Nucleus |
| Immunogen | A synthetic phosphorylated peptide around T183 & Y185 of human JNK1, JNK2 and JNK3 |
| Calculated MW | 27/35/44/48kDa |
| Observed MW | 46/54kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Unit | Piece |
| Y-Dilution Ratio | WB 1:1000-5000. IHC 1:50-200. IF 1:50-200. |
| Specification | 50ul 100ul |
| Reactivity | Human Mouse Rat |
| Application | WB IHC IF |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no experimental images.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
