Anti-AIFM1 Polyclonal Antibody
Cat.No:K112704P Solarbio
Reactivity:Human,Mouse,Rat
Application:WB,IHC
Clone Type:Polyclonal Antibody
Storage:Store at -20℃. Avoid freeze / thaw cycles.
Gene ID:9131
Host:Rabbit
Qty:
Size:
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My CartReactivity:Human,Mouse,Rat
Application:WB,IHC
Clone Type:Polyclonal Antibody
Storage:Store at -20℃. Avoid freeze / thaw cycles.
Gene ID:9131
Host:Rabbit
Qty:
Size:
Name | Anti-AIFM1 Polyclonal Antibody |
Host | Rabbit |
Clone Type | Polyclonal Antibody |
Subtype | IgG |
Dilution Ratio | WB 1:2000-5000. IHC 1:25-100. |
Target | AIFM1 |
Background | This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and motor-sensory defects with deafness and mental retardation. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. |
Swiss Prot | O95831 |
Gene ID | 9131 |
Subcellular Location | Cytoplasm Nucleus |
Immunogen | Recombinant protein of human AIFM1 |
Public Immunogen Range | 30-380aa |
Calculated MW | 5/28/35/36/66/67kDa |
Observed MW | 67kDa |
Purification Method | Affinity purification |
Storage Buffer | PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3. |
Storage | Store at -20℃. Avoid freeze / thaw cycles. |
Unit | Piece |
Specification | 20ul 50ul 100ul |
Reactivity | Human Mouse Rat |
Application | WB IHC |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder:Quick spin before use. If you have any questions, please contact us.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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