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My CartReactivity：Human,Mouse,Rat
Application：IHC,WB
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：5137
Host：Rabbit
Qty：
Size：
| Name | Anti-PDE1C Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Predicted Reactivity | Fruit fly |
| Dilution Ratio | WB 1:1000-3000. IHC 1:50-200. |
| Target | PDE1C |
| Background | This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta. |
| Swiss Prot | Q14123 |
| Gene ID | 5137 |
| Subcellular Location | Cytoplasm |
| Immunogen | Recombinant protein of human PDE1C |
| Public Immunogen Range | 285-635aa |
| Calculated MW | 72/81/87kDa |
| Observed MW | 72kDa |
| Purification Method | Octanoic acid-ammonium sulfate precipitation |
| Storage Buffer | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Unit | Piece |
| Specification | 20ul 50ul 100ul |
| Reactivity | Human Mouse Rat |
| Application | WB IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Western blot analysis with PDE1C antibody diluted at 1:2000;Lane: Rat kidney.
Immunohistochemistry of paraffin-embedded Human colorectal cancer with PDE1C antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human liver cancer with PDE1C antibody diluted at 1:100.
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