(S)-ML753286
Cat.No:IM4520 Solarbio
CAS:1699720-85-8
Molecular Formula:C20H25N3O3
Molecular Weight:355.43
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥98%
Appearance:Solid
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Small Molecule Compounds >
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(S)-ML753286CAS:1699720-85-8
Molecular Formula:C20H25N3O3
Molecular Weight:355.43
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥98%
Appearance:Solid
Qty:
Size:
CAS | 1699720-85-8 |
Name | (S)-ML753286 |
Molecular Formula | C20H25N3O3 |
Molecular Weight | 355.43 |
Solubility | Soluble in DMSO |
Purity | ≥98% |
Appearance | Solid |
Storage | Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year |
SMILES | CC1C(=O)N2C(CC3=C(C2CC(C)C)NC4=C3C=CC(=C4)OC)C(=O)N1 |
InChIKey | XDVXQQDQFWVCAU-GOPGUHFVSA-N |
InChI | InChI=1S/C20H25N3O3/c1-10(2)7-16-18-14(13-6-5-12(26-4)8-15(13)22-18)9-17-19(24)21-11(3)20(25)23(16)17/h5-6,8,10-11,16-17,22H,7,9H2,1-4H3,(H,21,24)/t11-,16-,17-/m0/s1 |
PubChem CID | 91669184 |
Target Point | BCRP |
Passage | Membrane Transporter&Ion Channel |
Background | (S)-ML753286 is a BCRP inhibitor. |
Biological Activity | (S)-ML753286 is a breast cancer resistance protein (BCRP) inhibitor with an IC50 of 0.6 μM on BCRP efflux transporter.[1] |
IC50 | IC50: 0.6μM(BCRP efflux transporter)[1] |
Data Literature Source | [1]. Li Y,et al. Synthesis of a new inhibitor of breast cancer resistance protein with significantly improved pharmacokinetic profiles. Bioorg Med Chem Lett. 2016 Jan 15;26(2):551-555. |
Unit | Bottle |
Specification | 5mg |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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