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My CartReactivity：Human,Mouse,Rat
Application：WB,IHC,IP
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：7166
Host：Rabbit
Qty：
Size：
| Name | Anti-TPH1 Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | WB 1:500-1000. IHC 1:50-100. IP 1:20. |
| Target | TPH1 |
| Background | Tryptophan hydroxylase (TPH) is the rate-limiting enzyme in the biosynthesis of serotonin by converting tryptophan to 5-hydroxy-L-tryptophan. Two isoforms of TPH exist: TPH-1 is mainly expressed in the periphery, whereas the expression of TPH-2 is restricted to neuronal cells and the central nervous system. Most of the serotonin found throughout the body is synthesized by TPH-1 in enterochromaffin cells of the gastrointestinal tract. Targeted disruption of the tph1 gene results in low levels of circulating and tissue serotonin. |
| Swiss Prot | P17752 |
| Gene ID | 7166 |
| Subcellular Location | Cytoplasm |
| Immunogen | A synthetic peptide of human TPH1 |
| Calculated MW | 51kDa |
| Observed MW | 51kDa |
| Purification Method | Affinity purification |
| Storage Buffer | Rabbit IgG in phosphate buffered saline，pH 7.4，150mM NaCl，0.02% sodium azide and 50% glycerol. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Unit | Piece |
| Specification | 50ul 100ul |
| Reactivity | Human Mouse Rat |
| Application | IP IHC WB |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Western blot analysis with TPH1 antibody diluted at 1:1000;Lane: THP-1.
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