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My CartReactivity：Mouse,Human
Application：IHC
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：152189
Host：Rabbit
Qty：
Size：
| Name | Anti-CMTM8 Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | IHC 1:50-200. |
| Target | CMTM8 |
| Background | CMTM8, also known as CKLFSF8, is a member of the chemokine-like factor superfamily (CKLFSF).Proteins of this family share similarity with both the chemokine and the transmembrane 4 superfamilies. CMTM8 is an attenuator of EGF-induced signaling (PMID: 16263120).Overexpression of CMTM8 accelerates ligand-induced clearance of EGFR from the cell surface and induces apoptosis via caspase-dependent and -independent pathways (PMID: 17149703).An alternative splice form of CMTM8, CMTM8-v2, arises from a deletion of exon 2. CMTM8-v2 maintains the ability to induce apoptosis (PMID: 17681841). |
| Swiss Prot | Q8IZV2 |
| Gene ID | 152189 |
| Subcellular Location | Cytoplasm Nucleus |
| Immunogen | A synthetic peptide of human CMTM8 |
| Public Immunogen Range | 110-160/173aa |
| Calculated MW | 13/20kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Unit | Piece |
| Specification | 20ul 50ul 100ul |
| Reactivity | Human Mouse |
| Application | IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Immunohistochemistry of paraffin-embedded Human renal cancer with CMTM8 antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human liver cancer with CMTM8 antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human pancreatic cancer with CMTM8 antibody diluted at 1:100.
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