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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Angiogenesis > PF-06459988CAS：1428774-45-1
Molecular Formula：C19H22ClN7O3
Molecular Weight：431.88
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
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| CAS | 1428774-45-1 |
| Name | PF-06459988 |
| Molecular Formula | C19H22ClN7O3 |
| Molecular Weight | 431.88 |
| Solubility | Soluble in DMSO ≥5mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | CN1C=C(C=N1)NC2=NC3=C(C(=CN3)Cl)C(=N2)OC[C@H]4CN(C[C@@H]4OC)C(=O)C=C |
| InChIKey | ODMXWZROLKITMS-RISCZKNCSA-N |
| InChI | InChI=1S/C19H22ClN7O3/c1-4-15(28)27-7-11(14(9-27)29-3)10-30-18-16-13(20)6-21-17(16)24-19(25-18)23-12-5-22-26(2)8-12/h4-6，8，11，14H，1，7，9-10H2，2-3H3，(H2，21，23，24，25)/t11-，14+/m1/s1 |
| PubChem CID | 71535003 |
| Target Point | EGFR |
| Passage | Angiogenesis;Protein Tyrosine Kinase/RTK |
| Background | PF-06459988 is an irreversible and mutant-selective EGFR mutant inhibitor with high titer and specificity against T790m-containing EGFRs double mutants. |
| Unit | Bottle |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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