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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Endocrinology & Hormones > (Rac)-PF-998425CAS：1076225-26-7
Molecular Formula：C14H14F3NO
Molecular Weight：269.26
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
Qty：
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| CAS | 1076225-26-7 |
| Name | (Rac)-PF-998425 |
| Molecular Formula | C14H14F3NO |
| Molecular Weight | 269.26 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | C1CCC(C(C1)C2=CC(=C(C=C2)C#N)C(F)(F)F)O |
| InChIKey | MENRRRXHFQYXDW-UHFFFAOYSA-N |
| InChI | InChI=1S/C14H14F3NO/c15-14(16，17)12-7-9(5-6-10(12)8-18)11-3-1-2-4-13(11)19/h5-7，11，13，19H，1-4H2 |
| PubChem CID | 25093229 |
| Target Point | Androgen Receptor |
| Passage | Endocrinology & Hormones |
| Background | (Rac)-PF-998425 is an effective and selective nonsteroidal androgen receptor (AR) antagonist. |
| Biological Activity | (Rac)-PF-998425 is a potent， selective， nonsteroidal androgen receptor (AR) antagonist. (Rac)-PF-998425 has IC50 values of 26 and 90 nM in the AR binding and cellular assays， respectively. (Rac)-PF-998425 has the potential for the research of the androgenetic alopecia[1]. |
| Data Literature Source | [1]. Li JJ，et al. Rational design and synthesis of 4-((1R，2R)-2-hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425)，a novel，nonsteroidal androgen receptor antagonist devoid of phototoxicity for dermatological indications. J Med Chem. 2008;51(21):7 |
| Unit | Bottle |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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