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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Angiogenesis > (E)-AG 99CAS：122520-85-8
Molecular Formula：C10H8N2O3
Molecular Weight：204.18
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 122520-85-8 |
| Name | (E)-AG 99 |
| Molecular Formula | C10H8N2O3 |
| Molecular Weight | 204.18 |
| Solubility | Soluble in DMSO ≥4mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00133901 |
| SMILES | C1=CC(=C(C=C1/C=C(C#N)/C(=O)N)O)O |
| InChIKey | USOXQZNJFMKTKJ-XVNBXDOJSA-N |
| InChI | InChI=1S/C10H8N2O3/c11-5-7(10(12)15)3-6-1-2-8(13)9(14)4-6/h1-4，13-14H，(H2，12，15)/b7-3+ |
| PubChem CID | 5328768 |
| Target Point | EGFR |
| Passage | Angiogenesis;Protein Tyrosine Kinase/RTK |
| Background | (E)-AG 99 is a potent EGFR inhibitor. |
| Biological Activity | (E)-AG 99 ((E)-Tyrphostin 46) is a potent EGFR inhibitor[1]. |
| Data Literature Source | [1]. Yamamoto N，et al. Tyrosine phosphorylation of p145met mediated by EGFR and Src is required for serum-independent survival of human bladder carcinoma cells. J Cell Sci. 2006 Nov 15;119(Pt 22):4623-33. |
| Unit | Bottle |
| Specification | 1mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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