{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Metabolic Enzyme & Protease > CVT-10216CAS：1005334-57-5
Molecular Formula：C24H19NO7S
Molecular Weight：465.48
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 1005334-57-5 |
| Name | CVT-10216 |
| Molecular Formula | C24H19NO7S |
| Molecular Weight | 465.48 |
| Solubility | Soluble in DMSO ≥2mg/mL(Need ultrasonic or Water bath) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD18072197 |
| SMILES | CS(=O)(=O)NC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)OCC4=CC(=CC=C4)C(=O)O |
| InChIKey | YYOOFJZTRCPVFD-UHFFFAOYSA-N |
| InChI | InChI=1S/C24H19NO7S/c1-33(29，30)25-18-7-5-16(6-8-18)21-14-32-22-12-19(9-10-20(22)23(21)26)31-13-15-3-2-4-17(11-15)24(27)28/h2-12，14，25H，13H2，1H3，(H，27，28) |
| PubChem CID | 23661666 |
| Target Point | aldehyde dehydrogenase (ALDH1/2) |
| Passage | Metabolic Enzyme&Protease |
| Background | CVT-10216 is a highly selective reversible aldehyde dehydrogenase 2 (ALDH-2) inhibitor that also has ALDH-1 inhibition. |
| Biological Activity | CVT-10216 is a highly selective， reversible aldehyde dehydrogenase-2 (ALDH-2) inhibitor with an IC50 of 29 nM. CVT-10216 also has inhibitory effect of ALDH-1 with an IC50 of 1.3 μM. CVT-10216 can reduce excessive alcohol drinking in alcohol-preferring rats and exhibit anxiolytic effects[1]. |
| IC50 | IC50: 29nM(ALDH-2)[1] |
| Data Literature Source | [1]. Overstreet DH，et al. A selective ALDH-2 inhibitor reduces anxiety in rats.Pharmacol Biochem Behav. 2009 Dec;94(2):255-61. |
| Unit | Bottle |
| Specification | 1mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
