{{cart_num}}
My CartReactivity：Human,Mouse,Rat
Application：IHC,WB
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：5521
Host：Rabbit
Qty：
Size：
| Name | Anti-PPP2R2B Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Predicted Reactivity | Bovine;Rabbit;Pig;Goldfish;Monkey;Gorilla |
| Dilution Ratio | WB 1:2000-5000. IHC 1:25-100. |
| Target | PPP2R2B |
| Background | The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases， and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme， which is composed of a catalytic subunit and a constant regulatory subunit， that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B55 subfamily. Defects in this gene cause autosomal dominant spinocerebellar ataxia 12 (SCA12)， a disease caused by degeneration of the cerebellum， sometimes involving the brainstem and spinal cord， and in resulting in poor coordination of speech and body movements. Multiple alternatively spliced variants， which encode different isoforms， have been identified for this gene. The 5’ UTR of some of these variants includes a CAG trinucleotide repeat sequence (7-28 copies) that can be expanded to 55-78 copies in cases of SCA12. |
| Swiss Prot | Q00005 |
| Gene ID | 5521 |
| Subcellular Location | Cytoplasm |
| Immunogen | Recombinant protein of human PPP2R2B |
| Public Immunogen Range | 1-444aa |
| Calculated MW | 52/52/58/59/63kDa |
| Observed MW | 47kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Unit | Piece |
| Specification | 20ul 50ul 100ul |
| Reactivity | Human Mouse Rat |
| Application | WB IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Western blot analysis with PPP2R2B antibody diluted at 1:3000;Lane: Raw264.7,C2C12,NIH3T3.
Immunohistochemistry of paraffin-embedded Human breast cancer with PPP2R2B antibody diluted at 1:50.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
