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My CartReactivity：Human
Application：FCM
Clone Type：Monoclonal Antibody
Storage：Store at 2-8℃. Avoid exposure to light.
Gene ID：5133
Host：Mouse
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| Name | Anti-CD279/PD-1(APC) Monoclonal Antibody |
| Host | Mouse |
| Clone Type | Monoclonal Antibody |
| Subtype | IgG1 |
| Dilution Ratio | FCM 5μL per test for million cells or whole blood in 100 μL volume. |
| Target | CD279 |
| Background | Programmed cell death 1 (PD-1)， also known as CD279， is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells， B cells， and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion. |
| Swiss Prot | Q15116 |
| Gene ID | 5133 |
| Subcellular Location | Cell membrane |
| Immunogen | A synthetic peptide of human CD279 |
| Calculated MW | 32kDa |
| Purification Method | Affinity purification |
| Storage Buffer | Liquid in PBS with 0.05% Proclin300，1% BSA. |
| Storage | Store at 2-8℃. Avoid exposure to light. |
| Unit | Piece |
| Specification | 100T |
| Reactivity | Human |
| Application | FCM |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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