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My CartReactivity：Mouse
Application：FCM
Clone Type：Monoclonal Antibody
Storage：Store at 2-8℃. Avoid exposure to light.
Gene ID：14960
Host：Rat
Qty：
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| Name | Anti-MHC Class II(FITC) Monoclonal Antibody |
| Host | Rat |
| Clone Type | Monoclonal Antibody |
| Subtype | IgG2b |
| Dilution Ratio | FCM 1X10^6 cells+0.2 ug |
| Target | MHC Class II |
| Background | Major histocompatibility complex (MHC) class II molecules are heterodimeric transmembrane glycoproteins that are expressed on the surface of antigen-presenting cells such as dendritic cells， macrophages， and B cells. The M5/114.15.2 antibody detects polymorphic determinants present on B cells， monocytes， macrophages， dendritic cells， and activated T lymphocytes from mice carrying the H-2b， H-2d， H-2q， H-2p， H-2r and H-2u haplotypes but not from mice carrying the H-2s or H-2f haplotypes (PMID: 6170707). This antibody recognizes both I-A and I-E subregion-encoded Ia glycoproteins (I-Ab， I-Ad， I-Aq， I-Ed， I-Ek， not I-Af， I-Ak， or I-As). M5/114 mAb is reported to inhibit I-A subregion-restricted T cell responses of the H-2b， H-2d， H-2q， H-2u but not the H-2f， H-2k， H-2s haplotypes (PMID: 6173436). |
| Swiss Prot | P14434 |
| Gene ID | 14960 |
| Subcellular Location | Cell membrane |
| Immunogen | Activated C57BL/6 mouse spleen cells |
| Purification Method | Affinity purification |
| Storage Buffer | Phosphate based buffer with 0.09% sodium azide and 0.1% gelatin，pH 7.2. |
| Storage | Store at 2-8℃. Avoid exposure to light. |
| Unit | Piece |
| Specification | 25ug 100ug |
| Reactivity | Mouse |
| Application | FCM |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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