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My CartReactivity：Mouse,Rat,Human
Application：WB,IHC
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：5832
Host：Rabbit
Qty：
Size：
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Predicted Reactivity | Orangutan |
| Dilution Ratio | WB 1:1000-3000.IHC 1:50-200. |
| Target | ALDH18A1 |
| Background | This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene. |
| Swiss Prot | P54886 |
| Gene ID | 5832 |
| Subcellular Location | Cytoplasm |
| Immunogen | Recombinant protein of human ALDH18A1 |
| Public Immunogen Range | 200-550aa |
| Calculated MW | 87kDa |
| Observed MW | 80kDa |
| Purification Method | Octanoic acid-ammonium sulfate precipitation |
| Storage Buffer | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Unit | Piece |
| Specification | 20ul 50ul 100ul |
| Reactivity | Mouse Rat Human |
| Application | WB IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Western blot analysis with ALDH18A1 antibody diluted at 1:2000;Lane: HepG2,NIH3T3,U-251MG,U-87MG,MCF7,U937.
Immunohistochemistry of paraffin-embedded Human endometrial cancer with ALDH18A1 antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human endometrial cancer with ALDH18A1 antibody diluted at 1:100.
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