Anti-GJB6 Polyclonal Antibody
Cat.No:K010492P Solarbio
Reactivity:Mouse,Human,Rat
Application:WB,IHC,IF
Clone Type:Polyclonal Antibody
Storage:Store at -20℃. Avoid freeze / thaw cycles.
Gene ID:10804
Host:Rabbit
Qty:
Size:
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My CartReactivity:Mouse,Human,Rat
Application:WB,IHC,IF
Clone Type:Polyclonal Antibody
Storage:Store at -20℃. Avoid freeze / thaw cycles.
Gene ID:10804
Host:Rabbit
Qty:
Size:
Name | Anti-GJB6 Polyclonal Antibody |
Host | Rabbit |
Clone Type | Polyclonal Antibody |
Subtype | IgG |
Dilution Ratio | WB 1:500-2000.IHC 1:50-200.IF 1:100-500. |
Target | GJB6 |
Background | The connexin family of proteins form hexameric complexes called connexons that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane alpha-helical domains, two extracellular loops, a cytoplasmic loop and cytoplasmic N- and C-termini. Many of the key functional differences between connexins arise from specific amino-acid substitutions in the most highly conserved domains: the transmembrane and extracellular regions. Connexin 30, also known as GJB6 (Gap junction beta 6), ED2, EDH, HED or DFNA3, is a 261 amino acid multi-pass membrane protein that localizes to the cell junction and belongs to the connexin family. Functioning as a hexamer with other connexin proteins, connexin 30 facilitates the diffusion of low molecular weight materials from one cell to another. Defects in the gene encoding connexin 30 are the cause of ectodermal dysplasia type 2 (ED2) and non-syndromatic sensorineural deafness autosomal dominant type 3 (DFNA3), the former of which is characterized by abnormal development of ectodermal structures (such as skin and nails). |
Swiss Prot | O95452 |
Gene ID | 10804 |
Subcellular Location | Cell membrane |
Immunogen | A synthetic peptide of human GJB6 |
Calculated MW | 29 kDa |
Purification Method | Affinity purification |
Storage Buffer | Rabbit IgG in phosphate buffered saline,pH 7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
Storage | Store at -20℃. Avoid freeze / thaw cycles. |
Unit | Piece |
Specification | 100ul |
Reactivity | Human Mouse Rat |
Application | WB IHC IF |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder:Quick spin before use. If you have any questions, please contact us.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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