T-5224
Cat.No:IT5020 Solarbio
CAS:530141-72-1
Molecular Formula:C29H27NO8
Molecular Weight:517.53
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥98%
Appearance:White to yellow Solid
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T-5224CAS:530141-72-1
Molecular Formula:C29H27NO8
Molecular Weight:517.53
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥98%
Appearance:White to yellow Solid
Qty:
Size:
CAS | 530141-72-1 |
Name | T-5224 |
Molecular Formula | C29H27NO8 |
Molecular Weight | 517.53 |
Solubility | Soluble in DMSO ≥10mg/mL(Need ultrasonic) |
Purity | ≥98% |
Appearance | White to yellow Solid |
Storage | Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year |
MDL | MFCD08272618 |
SMILES | C1CCC(C1)OC2=CC(=C(C=C2)C(=O)C3=CC(=C(C=C3)OCC4=CC5=C(C=C4)C(=O)NO5)CCC(=O)O)O |
InChIKey | DALCQQSLNPLQFZ-UHFFFAOYSA-N |
InChI | InChI=1S/C29H27NO8/c31-24-15-21(37-20-3-1-2-4-20)8-10-22(24)28(34)19-6-11-25(18(14-19)7-12-27(32)33)36-16-17-5-9-23-26(13-17)38-30-29(23)35/h5-6,8-11,13-15,20,31H,1-4,7,12,16H2,(H,30,35)(H,32,33) |
PubChem CID | 23626877 |
Target Point | AP-1 |
Passage | Others |
Background | T-5224 is a selective inhibitor of transcription factor c-Fos/activator protein (AP)-1, which has anti-inflammatory activity and can specifically inhibit the DNA-binding activity of c-Fos/c-Jun without affecting the binding activity of other transcription factors. T-5224 inhibited IL-1β-induced upregulation of Mmp-3, Mmp-13 and Adamts-5. |
Unit | Bottle |
Specification | 1mg |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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