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My CartReactivity：Human,Mouse,Rat
Application：IF,IHC,WB
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：340061
Host：Rabbit
Qty：
Size：
| Name | Anti-TMEM173 Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Predicted Reactivity | Pig;Bovine;Chicken |
| Dilution Ratio | WB 1:1000-3000. IHC 1:50-200. IF 1:50-200. |
| Target | TMEM173 |
| Background | This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. |
| Swiss Prot | Q86WV6 |
| Gene ID | 340061 |
| Subcellular Location | Cytoplasm Nucleus Secreted |
| Immunogen | Recombinant protein of human TMEM173 |
| Public Immunogen Range | 1-350aa |
| Calculated MW | 42kDa |
| Observed MW | 36kDa |
| Purification Method | Octanoic acid-ammonium sulfate precipitation |
| Storage Buffer | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Unit | Piece |
| Specification | 20ul 50ul 100ul |
| Reactivity | Human Mouse Rat |
| Application | WB IHC IF |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Western blot analysis with TMEM173 antibody diluted at 1:2000;Lane: U937,HT29,Mouse thymus,Mouse spleen.
Immunohistochemistry of paraffin-embedded Human colorectal cancer with TMEM173 antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human ovarian cancer with TMEM173 antibody diluted at 1:100.
Immunofluorescence analysis of HeLa cells using TMEM173 antibody diluted at 1:100.
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