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Application：ELISA
Reactivity：Human
Sample Type：Serum，Plasma，Cell Culture Supernatant
Sensitivity：39pg/mL
Storage：2-8℃，6 months
Gene ID：55554
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Size：
| Name | Human Kallikrein 15 ELISA Kit |
| Storage | 2-8℃，6 months |
| Detection Target | Kallikrein 15 |
| Sample Type | Serum，Plasma，Cell Culture Supernatant |
| Reactivity | Human |
| Application | ELISA |
| Quantitative/Qualitative | Quantitative |
| Detection Range | 78.125-5000pg/mL |
| Sensitivity | 39pg/mL |
| Precision | Both intra-plate and inter-plate variation coefficients were less than 10% |
| Recovery | 80%-120% |
| Swiss Prot | Q9H2R5 |
| Gene ID | 55554 |
| Background | The human tissue kallikrein (KLK) gene family contains 15 members that play important roles in cancer. Notably，kallikrein-1，also known as tissue kallikrein，cleaves kininogen to release the vasoactive kinin peptide，bradykinin or lysyl-bradykinin. Kallikrein-3，called prostate specific antigen (PSA)，is an established tumor marker that aids in the diagnosis，staging，and follow up of prostate cancer. Kallikrein-4 is specifically expressed in the prostate and over-expressed in prostate cancer. Kallikrein-5 is widely expressed but found at high levels in skin，breast，brain and testis; over-expression is an indicator of poor prognosis in ovarian cancer. Kallikrein-8 is expressed in the brain and is a novel marker of ovarian and cervical cancer.Human plasma kallikrein，a serine protease，is synthesized in the liver and circulates in the plasma bound to high molecular weight (HMW) kininogen or as a free zymogen. Once activated by its physiological activator，coagulation factor XII，it displays endopeptidase activity towards peptide bonds after arginine (preferred) and lysine. It cleaves HMW kininogen，its major physiological substrate，to release the potent vasodilator peptide bradykinin. It is also able to cleave a number of inactive precursor proteins to generate active products，such as plasminogen and prourokinase. |
| Unit | Kit |
| Specification | 48T 96T |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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