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My CartReactivity：Human,Rat,Mouse
Application：WB
Clone Type：Monoclonal Antibody
Storage：Store at -20℃. Avoid freeze/thaw cycles.
Gene ID：3953
Host：Rabbit
Qty：
Size：
| Name | Anti-Leptin Receptor Monoclonal Antibody |
| Host | Rabbit |
| Clone Type | Monoclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | WB 1:500-1000. |
| Target | Leptin Receptor |
| Background | The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight)，and is involved in the regulation of fat metabolism，as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons，however，encode distinct proteins (PMID:9207021). |
| Swiss Prot | P48357 |
| Gene ID | 3953 |
| Subcellular Location | Cell membrane Secreted Single-pass type I membrane protein |
| Immunogen | A synthetic peptide of human Leptin Receptor |
| Calculated MW | 132kDa |
| Observed MW | 150kDa |
| Purification Method | Affinity purification |
| Storage Buffer | Liquid in PBS containing 50% glycerol，150mM NaCl and 0.02% sodium azide，pH 7.4. |
| Storage | Store at -20℃. Avoid freeze/thaw cycles. |
| Unit | Piece |
| Specification | 50ul 100ul |
| Reactivity | Human Rat Mouse |
| Application | WB |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Western blot analysis with Leptin Receptor antibody diluted at 1:1000;Lane: SH-SY5Y.
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