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My CartReactivity：Human,Mouse
Application：IHC
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze/thaw cycles.
Gene ID：81846
Host：Rabbit
Qty：
Size：
| Name | Anti-SBF2 Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | IHC 1:50-200. |
| Target | SBF2 |
| Background | Guanine nucleotide exchange factor (GEF) which activates RAB21 and possibly RAB28 (PubMed:20937701，PubMed:25648148).Promotes the exchange of GDP to GTP，converting inactive GDP-bound Rab proteins into their active GTP-bound form (PubMed:20937701，PubMed:25648148).In response to starvation-induced autophagy，activates RAB21 which in turn binds to and regulates SNARE protein VAMP8 endolysosomal transport required for SNARE-mediated autophagosome-lysosome fusion (PubMed:25648148).Acts as an adapter for the phosphatase MTMR2 (By similarity).Increases MTMR2 catalytic activity towards phosphatidylinositol 3，5-bisphosphate and to a lesser extent towards phosphatidylinositol 3-phosphate (By similarity). |
| Swiss Prot | Q86WG5 |
| Gene ID | 81846 |
| Subcellular Location | Cytoplasm Cell membrane |
| Immunogen | Recombinant protein of human SBF2 |
| Public Immunogen Range | 1500-1850aa |
| Calculated MW | 129/208kDa |
| Purification Method | Octanoic acid-ammonium sulfate precipitation |
| Storage Buffer | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| Storage | Store at -20℃. Avoid freeze/thaw cycles. |
| Unit | Piece |
| Specification | 20ul 50ul 100ul |
| Reactivity | Human Mouse |
| Application | IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Immunohistochemistry of paraffin-embedded Human liver cancer with SBF2 antibody diluted at 1:100.
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